Mehrotra, Ranjana and Jangir, Deepak Kumar and Gupta, Alka and Kandpal, H. C. (2008) Differentiation of Normal and Malignant Breast Tissues using Infrared Spectroscopy. Perspectives in Vibrational Spectroscopy: ICOPVS 2008, 1075. pp. 141-143.

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Abstract

Infrared spectra of carcinomatous and their normal fore bearing tissues were collected in the 600 cm(-1) to 4000 cm(-1) region. Fourier Transform Infrared (FTIR) data of infiltrating ductal carcinoma of breast with different grades of malignancy from patients of different age groups were analyzed. Infrared spectra demonstrate significant spectral differences between the tumor sections of normal and the malignant breast tissues. In particular, changes in frequency and intensity in the spectra of protein, nucleic acid and glycogen were observed. This allows to make a qualitative and semi quantitative evaluation of the changes in proliferation activities from normal to diseased tissue. The findings establish a framework for additional studies, which may enable us to establish a relation of the diseased state with its infrared spectra.

Item Type:	Article
Subjects:	Spectroscopy
Divisions:	UNSPECIFIED
Depositing User:	Ms Neetu Chandra
Date Deposited:	10 Jul 2013 09:50
Last Modified:	10 Jul 2013 09:50
URI:	http://npl.csircentral.net/id/eprint/977

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