Solanki, Pratima R. and Prabhakar, Nirmal and Pandey, Manoj K. and Malhotra, Bansi D. (2008) Surface plasmon resonance-based DNA biosensor for arsenic trioxide detection. International Journal of Environmental Analytical Chemistry , 89 (1). pp. 49-57. ISSN 1029–0397

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Abstract

Surface plasmon resonance-based biosensor has been fabricated using self-assembled monolayer (SAM) of β-merceptoethanol (MCE) deposited on gold (Au) substrate. The double stranded calf thymus deoxyribonucleic acid (dsCT-DNA) has been immobilised onto MCE/Au electrode using N-ethyl-N′-(3-dimethylaminopropyl) carbodiimide and N-hydroxysuccinimide (EDC/NHS) chemistry. This dsCT-DNA/MCE/Au bioelectrode has been characterised using cyclic voltammetry, scanning electron microscopy (SEM) and X-ray photoelectron spectrometry (XPS), respectively. The detection limit of arsenic trioxide has been estimated as 0.01 × 10−6 g mL−1.

Item Type:	Article
Additional Information:	Copyright for this article belongs to M/s Taylor & Francis.
Subjects:	Chemistry
Divisions:	UNSPECIFIED
Depositing User:	Ms Neetu Chandra
Date Deposited:	12 Oct 2012 12:30
Last Modified:	12 Oct 2012 12:30
URI:	http://npl.csircentral.net/id/eprint/690

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