Solanki, Pratima R. and Kaushik, Ajeet and Ansari, Anees A. and Malhotra , B. D. (2009) Nanostructured zinc oxide platform for cholesterol sensor. Applied Physics Letters, 94 (14). pp. 143901-1. ISSN 1077-3118

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Abstract

Nanostructured zinc oxide (nano-ZnO) film has been fabricated onto indium tin oxide (ITO) containing preferred (002) plane and 10 nm crystallite size using sol-gel technique for immobilization of cholesterol oxidase (ChOx). Electrochemical response of ChOx/nano-ZnO/ITO bioelectrode determined as a function of cholesterol concentration using cyclic voltammetry technique reveals improved detection range (5–400 mg/dl), low detection limit (0.5 mg/dl), fast response time (10 s), sensitivity (0.059 μA/mg dl−1 cm−2), and low value (0.98 mg/dl) of Michaelis–Menten constant (Km). It is shown that nano-ZnO film provides better environment and enhanced electron transfer between ChOx and electrode.

Item Type: Article
Additional Information: Copyright for this article belongs to M/s Elsevier B.V.
Subjects: Physics
Divisions: UNSPECIFIED
Depositing User: Ms Neetu Chandra
Date Deposited: 20 Sep 2012 11:56
Last Modified: 20 Sep 2012 12:02
URI: http://npl.csircentral.net/id/eprint/579

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