Malhotra, Bansi D. and Kaushik, Ajeet (2009) Metal oxide–chitosan based nanocomposite for cholesterol biosensor. Thin Solid Films, 518 (2). pp. 614-620. ISSN 0040-6090

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Abstract

Metal oxide [cerium oxide (NanoCeO2)]–chitosan (CH) nanocomposite film has been fabricated onto indium-tin-oxide (ITO) coated glass plate to immobilize cholesterol oxidase (ChOx) via physiosorption for cholesterol detection. Electrochemical studies reveal that the presence of NanoCeO2 in CH–CeO2 nanocomposite results in increased electroactive surface area for ChOx loading resulting in enhanced electron transport between ChOx and electrode. The ChOx/CH–NanoCeO2/ITO bioelectrode exhibits interesting characteristics such as detection range of 10–400 mg/dL, detection limit of 5 mg/dL, response time of 10 s, low Km value of 3.5 mg/dL and value of regression coefficient of 0.994.

Item Type:	Article
Additional Information:	Copyright for this article belongs to M/s Elsevier B.V.
Uncontrolled Keywords:	CeO2 nanoparticles; Chitosan; Nanocomposite; Cholesterol biosensor
Subjects:	Materials Science Physics
Divisions:	UNSPECIFIED
Depositing User:	Ms Neetu Chandra
Date Deposited:	11 Sep 2012 09:10
Last Modified:	11 Sep 2012 09:10
URI:	http://npl.csircentral.net/id/eprint/562

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