Radhakrishnan, Venkatraman Srinivasan and Mudiam, Mohana Krishna Reddy and Kumar, Manish and Dwivedi, Surya Prakash and Singh, Surinder Pal and Prasad, Tulika (2018) Silver nanoparticles induced alterations in multiple cellular targets, which are critical for drug susceptibilities and pathogenicity in fungal pathogen (Candida albicans). International Journal of Nanomedicine, 13. pp. 2647-2663. ISSN 1178-2013

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Abstract

Purpose: A significant increase in the incidence of fungal infections and drug resistance has been observed in the past decades due to limited availability of broad-spectrum antifungal drugs. Nanomedicines have shown significant antimicrobial potential against various drug-resistant microbes. Silver nanoparticles (AgNps) are known for their antimicrobial properties and lower host toxicity; however, for clinical applications, evaluation of their impact at cellular and molecular levels is essential. The present study aims to understand the cellular and molecular mechanisms of AgNp-induced toxicity in a common fungal pathogen, Candida albicans.

Item Type:	Article
Additional Information:	Copyright for this article belongs to M/s Dove Medical Press.
Subjects:	Nanoscience/ Nanotechnology Pharmacology & Pharmacy
Divisions:	UNSPECIFIED
Depositing User:	Users 27 not found.
Date Deposited:	20 Dec 2019 07:16
Last Modified:	20 Dec 2019 07:16
URI:	http://npl.csircentral.net/id/eprint/3743

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