Tyagi, Mukta and Choudhary, Amit and Upadhyay, Santosh K. and Agrawal, Ved V. and Biradar, A. M. (2017) Dielectric behaviour of neutrophil gelatinase associated lipocalin detected by alpha relaxation process. Integrated Ferroelectrics, 184 (1). pp. 55-68. ISSN 1058-4587

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Abstract

We have investigated alpha () relaxation process and its temperature evolution in electrical double layer (EDL) around neutrophil gelatinase-associated lipocalin (NGAL), anti-lipocalin2 (anti-LCN-2) and their conjugate in phosphate buffer. The dielectric permittivity (20Hz to 1MHz) of -relaxation process for LCN-2 and anti-LCN-2 shows variation with temperature. This happens due to unfolding of various microstates of protein at measured temperature intervals. The DSC thermograms of LCN-2, anti-LCN-2 and their conjugate predict that the multiple unfolding domains are parallel to the shifts in real dielectric permittivity at a particular temperature.

Item Type:	Article
Additional Information:	Copyright for this article belongs to M/s Taylor & Francis.
Subjects:	Engineering > Electronics and Electrical Engineering Applied Physics/Condensed Matter
Divisions:	UNSPECIFIED
Depositing User:	Users 27 not found.
Date Deposited:	31 Aug 2018 06:44
Last Modified:	31 Aug 2018 06:44
URI:	http://npl.csircentral.net/id/eprint/2659

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