Singh, Anu and Choudhary, Meenakshi and Kaur, Satbir and Singh, Surinder P. and Arora, Kavita (2016) Molecular Functionalization of Carbon Nanomaterials for Immuno-diagnosis of Cancer. Materials Today: Proceedings , 3 (2). 157-161 . ISSN 2214-7853

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Abstract

Carbon nanomaterials possess amazing physico-chemical properties with great potential for molecular functionalization to construct sensitive biosensors. We report a study of graphene oxide (GO) and carbon nanotubes (CNTs), to achieve, reusable, low cost and efficient immuno-sensing platform for lung cancer. Presence of biomarker (hTERT) was detected in concentration range of 10 ag mL(-1) -50 ng mL(-1) and 5 fg mL(-1) -50 ng mL(-1) using GO and CNT based nanocomposites, respectively. Subsequently, due to favourable attributes (peak current, stability, repeatability and reproducibility) achieved through CNT, simultaneous bianalyte detection of biomarkers (MAGE A2/A11)) expressed in serum, were demonstrated.

Item Type:	Article
Additional Information:	Copyright for this article belongs to M/s Elsevier.
Uncontrolled Keywords:	Carbon Nanotubes, Graphene Oxide, chitosan, Lung Cancer, Immunosensor
Subjects:	Materials Science > Materials Science
Divisions:	UNSPECIFIED
Depositing User:	Dr. Rajpal Walke
Date Deposited:	01 Feb 2018 07:05
Last Modified:	01 Feb 2018 07:05
URI:	http://npl.csircentral.net/id/eprint/2280

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