Sharma, Vikash and Kumar, Ajay and Ganguly, Prasun and Biradar, A. M.
(2014)
Highly sensitive bovine serum albumin biosensor based on liquid crystal.
Applied Physics Letters, 104 (4).
ISSN 0003-6951
Abstract
A highly sensitive liquid crystal (LC) based bovine serum albumin (BSA) protein biosensor is designed. A uniform homeotropic alignment of nematic LC was observed in BSA free substrate which changed into homogeneous in presence of BSA. The change in the LC orientation is found to depend strongly on BSA concentration. This change in the LC alignment is attributed to the modification in the surface conditions which is verified by contact angle measurements. We have detected an ultra low concentration (0.5 mu g/ml) of BSA. The present study demonstrates the utilization of LC in the realization of high sensitivity biosensors.
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