Singh, Shalini and Sharma, Shailesh N. and -, Govind and Shivaprasad, S. M. and Lal, Mohan and Khan, Mukhtar A. (2008) Nanostructured porous silicon as functionalized material for biosensor application. Journal of Materials Science: Materials in Medicine , 20. pp. 181-187. ISSN 1573-4838

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In this work by means of PL, FTIR and XPS techniques, state-of-the-art porous silicon (PS) films with good mechanical and optical properties have been effectively utilized for the biofunctionalization purpose for its possible application in immunosensors. The functionalization of the PS surface has been achieved by silanization process using aminopropyltriethoxysilane (APTS) as a precursor. The presence of reactive amino groups on the PS surface along with glutaraldehyde as a linker aids in the covalent binding of the antibody (Human IgG) onto the PS surface. Different antigen concentrations can be detected with a good reproducibility with this technique which opens a huge possibility of using this biofunctionalized material for future biosensors.

Item Type: Article
Additional Information: Copyright for this article belongs to M/s Springer Verlag.
Subjects: Engineering
Materials Science
Depositing User: Ms Neetu Chandra
Date Deposited: 19 Sep 2012 12:31
Last Modified: 19 Sep 2012 12:31

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