Saha, Shibu and Arya, Sunil K. and Singh, S. P. and Sreenivas, K. and Malhotra, B. D. and Gupta, Vinay (2009) Nanoporous cerium oxide thin film for glucose biosensor. Biosensors and Bioelectronics, 24 (7). pp. 2040-2045. ISSN 0956-5663

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Abstract

Nanoporous cerium oxide (CeO2) thin film deposited onto platinum (Pt) coated glass plate using pulsed laser deposition (PLD) has been utilized for immobilization of glucose oxidase (GOx). Atomic force microscopy studies reveal the formation of nanoporous surface morphology of CeO2 thin film. Response studies carried out using differential pulsed voltammetry (DPV) and optical measurements show that the GOx/CeO2/Pt bio-electrode shows linearity in the range of 25–300 mg/dl of glucose concentration. The low value of Michaelis-Menten constant (1.01 mM) indicates enhanced enzyme affinity of GOx to glucose. The observed results show promising application of the nanoporous CeO2 thin film for glucose sensing application without any surface functionalization or mediator.

Item Type:	Article
Additional Information:	Copyright for this article belongs to M/s Elsevier B.V.
Uncontrolled Keywords:	Glucose; Cerium oxide; Biosensor
Subjects:	Biochemistry & Molecular Biology Biophysics Biotechnology & Applied Microbiology Electrochemistry
Divisions:	UNSPECIFIED
Depositing User:	Ms Neetu Chandra
Date Deposited:	18 Sep 2012 12:51
Last Modified:	18 Sep 2012 12:51
URI:	http://npl.csircentral.net/id/eprint/574

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