Verma, Shilpi and Singh, Surinder P.
(2019)
Non-invasive oral cancer detection from saliva using zinc oxide-reduced graphene oxide nanocomposite based bioelectrode.
MRS Communications, 9 (4).
pp. 1227-1234.
ISSN 2159-6859
Abstract
Multifunctional materials with excellent biocompatibility and electron-transport properties are critical for the pursuit of point-of-care biosensing devices. The authors report the synthesis of zinc oxide-reduced graphene oxide (ZnO-rGO) nanocomposite for the fabrication of an electrochemical immunosensing test-bed for noninvasive onsite detection of oral cancer biomarker (interleukin-8, IL8). The immunosensor showed successful detection of IL8 at low concentration ranges, i.e., 100 fg/mL-5 ng/mL with a sensitivity of 12.46 +/- 0.82 mu A mL/ng and a detection limit of 51.53 +/- 0.43 pg/mL. These results have been validated through in vitro investigations using real saliva samples spiked with IL8.
| Item Type: |
Article
|
| Additional Information: |
Copyright for this article belongs to M/s Materials Research Society. |
| Subjects: |
Materials Science |
| Divisions: |
UNSPECIFIED |
| Depositing User: |
Mr. Yogesh Joshi
|
| Date Deposited: |
14 Jul 2021 11:40 |
| Last Modified: |
14 Jul 2021 11:40 |
| URI: |
http://npl.csircentral.net/id/eprint/4401 |
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