Singh, Shalini and Lapin, Norman and Singh , P. K. and Khan, Mukhtar A. and Chabal, Yves J. (2009) Attachment Of Streptavidin-Biotin On 3-Aminopropyltriethoxysilane (APTES) Modified Porous Silicon Surfaces. In: International Conference on Transport and Optical Properties of Nanomaterials (ICTOPON 2009) , JAN 05-08, 2009 , Allahabad, INDIA.

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Nanostructured porous silicon (PS) has a large surface area that can be well controlled and modified to have a high specificity for biomolecules. These properties make it a very promising biomaterial, in particular for sensing devices that need to be linked to the biological system and completely compatible with standard integrated circuit processes. We report the formation of nanostructured PS on boron doped, p-type silicon (100) wafers by electrochemical anodization, using aqueous hydrofluoric acid and isopropyl alcohol solutions and a constant current density 50 mA/cm2. The pore diameter can be tuned by varying the etching conditions. The interaction of streptavidin with biotin was studied on 3-aminopropyltriethoxysilane (APTES) functionalized PS surfaces using infrared absorption spectroscopy to characterize the surface at each step, including subsequent reaction steps. These studies show that the streptavidin-biotin interaction on modified PS surfaces depends on the details of the APTES adsorption process.

Item Type: Conference or Workshop Item (Paper)
Subjects: Optics
Depositing User: Ms Neetu Chandra
Date Deposited: 13 Aug 2012 12:45
Last Modified: 13 Aug 2012 12:45

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