Das, Maumita and Dhand, Chetna and Sumana, Gajjala and Srivastava, Avanish Kumar and Nagarajan, Rajamani and Malhotra, Bansi Dhar (2012) Electrophoretically fabricated core-shell CNT-DNA biowires for biosensing. Journal of Materials Chemistry , 22 (6). pp. 2727-2732. ISSN 0959-9428

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In view of recent revelations and potential applications of the carbon nanotubes (CNT)-deoxyribonucleic acid (DNA) nanobiohybrids, we propose a mechanism of DNA wrapping onto functionalized CNT using principles of co-ordination chemistry. The core-shell structural biowire comprising of CNT and DNA has been fabricated via electrophoretic deposition technique and detailed morphological investigations have been carried out to ascertain the mechanism of biowire formation. The results of these studies reveal that during the biowire formation, Mg2+ ions provide the central metal ion with enhanced structural and catalytic activity for DNA and CNT to covalently co-ordinate to form a bi-cyclic chelate structure. Employing the synergy between the nanomaterial and biomolecule, DNA-Mg2+-CNT biowires can be used as a nanobioelectrode platform for development of a genosensor.

Item Type: Article
Additional Information: Copyright for this article belongs to M/s Royal Society of Chemistry.
Subjects: Materials Science
Physical Chemistry/Chemical Physics
Depositing User: Users 27 not found.
Date Deposited: 04 Mar 2020 11:30
Last Modified: 04 Mar 2020 11:30
URI: http://npl.csircentral.net/id/eprint/3592

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