Narayanan, Tharangattu N. and Gupta, Bipin K. and Vithayathil, Sajna A. and Aburto, Rebeca R. and Mani, Sendurai A. and Taha-Tijerina, Jaime and Xie, Bin and Kaipparettu, Benny A. and Torti, Suzy V. and Ajayan, Pulickel M. (2012) Hybrid 2D Nanomaterials as Dual-Mode Contrast Agents in Cellular Imaging. Advanced Materials, 24 (22). pp. 2992-2998. ISSN 0935-9648

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The design of multifunctional nanofluids is highly desirable for biomedical therapy/cellular imaging applications.[1–4] The emergence of hybrid nanomaterials with specific properties, such as magnetism and fluorescence, can lead to an understanding of biological processes at the biomolecular level.[1] Various hybrid systems have been analyzed in the recent past for several possible biomedical applications.[5–9] Carbon-based hybrid systems such as carbon nanotubes with various nanoparticles are being widely tested for their biological applications because of their ability to cross cell membranes and their interesting thermal and electrical properties.[10,11] Graphene oxide (GO) is a fairly new graphene-based system with a 2D carbon honeycomb lattice decorated with numerous functional groups attached to the backbone: these functional groups make it an excellent platform for further attachment of nanoparticles and synthesis of hybrid materials. Cell viability studies on GO have been recently attempted, showing biocompatibility. [12,13] Moreover, the intrinsic photoluminescence (PL) properties of GO can be utilized for cellular imaging.[13] The large surface area and non-covalent interactions with aromatic molecules make GO an excellent system for biomolecular applications and drug attachment.

Item Type: Article
Additional Information: Copyright for this article belongs to M/s Wiley.
Subjects: Chemistry
Materials Science
Applied Physics/Condensed Matter
Nanoscience/ Nanotechnology
Physical Chemistry/Chemical Physics
Depositing User: Users 27 not found.
Date Deposited: 12 Mar 2020 11:26
Last Modified: 12 Mar 2020 11:26

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