Attri, Pankaj and Bhatia, Rohit and Gaur, Jitender and Arora, Bharti and Gupta, Anjali and Kumar, Naresh and Choi, Eun Ha (2017) Triethylammonium acetate ionic liquid assisted one-pot synthesis of dihydropyrimidinones and evaluation of their antioxidant and antibacterial activities. Arabian Journal of Chemistry, 10 (2). pp. 206-214. ISSN 1878-5352

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A mild and efficient catalytic method has been developed to synthesize 3,4-dihydropyrimidinones in high yield by one-pot three component Biginelli condensation in the presence of triethylammonium acetate (TEAA) which acts as catalyst/reaction medium. Further, we have studied the antioxidant and antibacterial activities of these synthesized 3,4-dihydropyrimidinones. All the synthesized compounds reveal the significant antioxidant properties, these properties have been studied using 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging and cupric reducing antioxidant capacity (CUPRAC) assays. In addition, to this, these compounds also show the good antibacterial activity against four human pathogenic bacteria. (C) 2014 King Saud University.

Item Type: Article
Additional Information: Copyright for this article belongs to M/S Elsevier.
Subjects: Chemistry
Depositing User: Users 27 not found.
Date Deposited: 30 May 2019 11:21
Last Modified: 30 May 2019 11:21

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