Gao, Zhaoli and Kang, Hojin and Naylor, Carl H. and Streller, Frank and Ducos, Pedro and Serrano, Madeline D. and Ping, Jinglei and Zauberman, Jonathan and Rajesh, Dr and Carpick, Robert W. and Wang, Ying-Jun and Park, Yung Woo and Luo, Zhengtang and Ren, Li and Johnson, A. T. Charlie (2016) Scalable Production of Sensor Arrays Based on High-Mobility Hybrid Graphene Field Effect Transistors. ACS Applied Materials and Interfaces , 8 (41). 27546-27552 . ISSN 1944-8244

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We have developed a scalable fabrication process for the production of DNA biosensors based on gold nanoparticle-decorated graphene field effect transistors (AuNP-Gr-FETs), where monodisperse AuNPs are created through physical vapor deposition followed by thermal annealing. The FETs are created in a four-probe configuration, using an optimized bilayer photolithography process that yields chemically clean devices, as confirmed by XPS and AFM, with high carrier mobility (3590 +/- 710 cm2/V.s) and low unintended doping (Dirac voltages of 9.4 +/- 2.7 V). The AuNP-Gr-FETs were readily functionalized with thiolated probe DNA to yield DNA biosensors with a detection limit of 1 nM and high specificity against noncomplementary DNA. Our work provides a pathway toward the scalable fabrication of high-performance AuNP-Gr-FET devices for label-free nucleic acid testing in a realistic clinical setting.

Item Type: Article
Additional Information: Copyright for this article belongs to M/s American Chemical Society.
Subjects: Materials Science
Nanoscience/ Nanotechnology
Depositing User: Dr. Rajpal Walke
Date Deposited: 17 Apr 2018 12:08
Last Modified: 17 Apr 2018 12:08

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