Matharu, Zimple and Sumana, G. and Gupta, Vinay and Malhotra, B. D. (2010) Langmuir–Blodgett films of polyaniline for low density lipoprotein detection. Thin Solid Films, 519 (3). pp. 1110-1114. ISSN 0040-6090

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Langmuir–Blodgett (LB) films of polyaniline (PANI) were utilized for the fabrication of impedimetric immunosensor for detection of human plasma low density lipoprotein (LDL) by immobilizing anti-apolipoprotein B (AAB) via EDC–NHS coupling. The modified electrodes were characterized by electrochemical impedance spectroscopy (EIS) and scanning electron microscopy. AAB/PANI–SA LB immunoelectrodes studied by EIS spectroscopy revealed detection of LDL in the wide range of 0.018 μM (6 mg/dl) to 0.39 μM (130 mg/dl), covering the physiological range in blood, with a sensitivity of 11.25 kΩ μM− 1.

Item Type: Article
Additional Information: Copyright for this article belongs to M/s Elsevier B.V.
Uncontrolled Keywords: Langmuir–Blodgett; Low density lipoprotein; Immunosensor; Electrochemical impedance spectroscopy
Subjects: Materials Science
Depositing User: Ms Neetu Chandra
Date Deposited: 18 May 2012 07:57
Last Modified: 18 May 2012 07:57

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